Latest Medical News – Oncology

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NEJM Journal Watch: Oncology And Hematology RSS Feed Summaries of and commentary on oncology and hematology medical journal articles covering topics such as breast cancer, gastrointestinal cancer, genitourinary cancer, lung cancer, head and neck cancers, malignant hematology, and benign hematology.

Radiation Therapy and Risk for Contralateral Breast Cancer
by William J. Gradishar, MD on 02/12/2023 at 6:29 AM
In women who have BRCA1/2 mutations and primary breast cancer, radiation therapy might increase the risk for cancer in the other breast.
First-Line Selpercatinib in RET Fusion-Positive NSCLC
by Jyoti D. Patel, MD, FASCO on 02/12/2023 at 6:29 AM
Progression-free survival was longer with selpercatinib than with platinum-based chemotherapy plus pemetrexed with or without pembrolizumab.
Pembrolizumab plus Chemotherapy for Patients with Advanced Gastric Cancer?
by David H. Ilson, MD, PhD on 02/12/2023 at 6:29 AM
Adding an immune checkpoint inhibitor to first-line chemotherapy improves overall survival, but only in patients with combined positive scores of ≥1% for PD-L1.
Sotorasib plus Panitumumab for Mutated KRAS G12C Metastatic Colon Cancer
by David H. Ilson, MD, PhD on 02/12/2023 at 6:29 AM
This combination resulted in higher PFS and response rates than trifluridine-tipiracil or regorafenib.
Pembrolizumab plus Chemotherapy for Pleural Mesothelioma
by Jyoti D. Patel, MD, FASCO on 02/12/2023 at 6:29 AM
The addition of pembrolizumab to platinum-based chemotherapy improved overall survival compared with chemotherapy alone in patients with advanced pleural mesothelioma.

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